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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50062749'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50062749
PNG
(CHEMBL3397784)
Show SMILES CCCCCC(=O)N(C)c1ccc(cc1)C12CC3CC(CC(C3)(C1)c1ccc(cc1)C#N)C2 |TLB:12:15:18:22.20.21,24:21:18.19.32:16,THB:23:21:18:32.15.16,23:15:18:22.20.21,24:21:18:32.15.16,20:19:16:22.21.23,20:21:18.19.32:16|
Show InChI InChI=1S/C30H36N2O/c1-3-4-5-6-28(33)32(2)27-13-11-26(12-14-27)30-18-23-15-24(19-30)17-29(16-23,21-30)25-9-7-22(20-31)8-10-25/h7-14,23-24H,3-6,15-19,21H2,1-2H3
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Similars
Article
PubMed
n/an/a 125n/an/an/an/an/an/a



Tokyo Medical and Dental University

Curated by ChEMBL


Assay Description
Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-inducted alkaline phosphatase expression after 24 hrs by plate r...

Bioorg Med Chem 23: 803-9 (2015)


Article DOI: 10.1016/j.bmc.2014.12.047
BindingDB Entry DOI: 10.7270/Q2XG9SS2
More data for this
Ligand-Target Pair