BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50066523'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
Scientific Computing Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Baculovirus-Expressed hPR-A				J Med Chem 41: 3461-6 (1998) Article DOI: 10.1021/jm9801915 BindingDB Entry DOI: 10.7270/Q2KD1ZKM
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...				Bioorg Med Chem Lett 12: 3487-90 (2002) BindingDB Entry DOI: 10.7270/Q2R210RC
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Inhibition of human progesterone receptor				J Med Chem 48: 5092-5 (2005) Article DOI: 10.1021/jm050358b BindingDB Entry DOI: 10.7270/Q2FF3RXG
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cells				J Med Chem 41: 3461-6 (1998) Article DOI: 10.1021/jm9801915 BindingDB Entry DOI: 10.7270/Q2KD1ZKM
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair