Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50292774'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50292774 (17beta-Hydroxy-11beta-[4-(1-oxo-5-methoxycarbonyl-...) Show SMILES COC(=O)CCCCC(=O)N(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:35,42| Show InChI InChI=1S/C35H43NO5/c1-5-19-35(40)20-18-30-28-16-12-24-21-26(37)15-17-27(24)33(28)29(22-34(30,35)2)23-10-13-25(14-11-23)36(3)31(38)8-6-7-9-32(39)41-4/h10-11,13-14,21,28-30,40H,6-9,12,15-18,20,22H2,1-4H3/t28-,29+,30-,34-,35-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
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