Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand/protein 1' and Ligand = 'BDBM474556'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human))	BDBM474556 (US10882844, Example 1016) Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3CCCC[C@H]3C(O)=O)cc2Cl)cccc1-c1ccc2oc(nc2c1)C1CCN(CC(O)=O)CC1 |r| Show InChI InChI=1S/C42H42ClN5O7/c1-26-31(5-4-6-33(26)30-8-9-37-35(17-30)46-41(55-37)29-10-13-47(14-11-29)23-40(49)50)25-54-39-18-38(53-24-28-15-27(19-44)20-45-21-28)32(16-34(39)43)22-48-12-3-2-7-36(48)42(51)52/h4-6,8-9,15-18,20-21,29,36H,2-3,7,10-14,22-25H2,1H3,(H,49,50)(H,51,52)/t36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US10882844 (2021) BindingDB Entry DOI: 10.7270/Q26113F8
					More data for this Ligand-Target Pair