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Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand 1' and Ligand = 'BDBM365896'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))		BDBM365896
PNG
(2-{3,5-dimethoxy-4-[(2- methylpyrrolidin-1- yl)met...)
Show SMILES COc1cc(OCc2cccc(-c3ccccc3)c2C#N)cc(OC)c1CN1CCCC1C
Show InChI InChI=1S/C28H30N2O3/c1-20-9-8-14-30(20)18-26-27(31-2)15-23(16-28(26)32-3)33-19-22-12-7-13-24(25(22)17-29)21-10-5-4-6-11-21/h4-7,10-13,15-16,20H,8-9,14,18-19H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/an/an/a



Novartis Pharmaceuticals



Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...

J Med Chem 51: 4-16 (2008)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair