Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Homo sapiens (Human)) | BDBM446465 ((R)-1-((7-cyano-2-(3′-(2-(difluoromethyl)-7-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation US Patent | Assay Description The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in... | US Patent US10669271 (2020) BindingDB Entry DOI: 10.7270/Q2MG7SJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Homo sapiens (Human)) | BDBM446465 ((R)-1-((7-cyano-2-(3′-(2-(difluoromethyl)-7-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Homo sapiens (Human)) | BDBM446465 ((R)-1-((7-cyano-2-(3′-(2-(difluoromethyl)-7-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation US Patent | Assay Description The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in... | US Patent US10669271 (2020) BindingDB Entry DOI: 10.7270/Q2MG7SJC | |||||||||||
More data for this Ligand-Target Pair |