Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Homo sapiens (Human)) | BDBM461612 (US10774071, Example B-79) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0640 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra... | US Patent US10774071 (2020) BindingDB Entry DOI: 10.7270/Q2CV4MTC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Homo sapiens (Human)) | BDBM461612 (US10774071, Example B-79) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description Compounds were tested in a functional co-culture reporter assay in which TCR-mediated NFAT activity is inhibited by the engagement of PD-1 with PD-L1... | US Patent US10774071 (2020) BindingDB Entry DOI: 10.7270/Q2CV4MTC | |||||||||||
More data for this Ligand-Target Pair |