Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prokineticin receptor 1' and Ligand = 'BDBM250591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250591 (US10167273, Example 70 | US10544126, Example 70 | ...) Show SMILES Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H21Cl2N3O3S/c1-11-16(12(2)21-20-11)26(24,25)22-7-5-17(23,6-8-22)10-13-3-4-14(18)15(19)9-13/h3-4,9,23H,5-8,10H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	7.4	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9475795 (2016) BindingDB Entry DOI: 10.7270/Q20Z727W
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250591 (US10167273, Example 70 | US10544126, Example 70 | ...) Show SMILES Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H21Cl2N3O3S/c1-11-16(12(2)21-20-11)26(24,25)22-7-5-17(23,6-8-22)10-13-3-4-14(18)15(19)9-13/h3-4,9,23H,5-8,10H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of a compound to block the intracellular release of calcium mediated by PK1 in RBL2H3 cells expressing human PKR1 receptors is determined...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4NKN
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250591 (US10167273, Example 70 | US10544126, Example 70 | ...) Show SMILES Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H21Cl2N3O3S/c1-11-16(12(2)21-20-11)26(24,25)22-7-5-17(23,6-8-22)10-13-3-4-14(18)15(19)9-13/h3-4,9,23H,5-8,10H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10544126 (2020) BindingDB Entry DOI: 10.7270/Q2MP55NK
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250591 (US10167273, Example 70 | US10544126, Example 70 | ...) Show SMILES Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H21Cl2N3O3S/c1-11-16(12(2)21-20-11)26(24,25)22-7-5-17(23,6-8-22)10-13-3-4-14(18)15(19)9-13/h3-4,9,23H,5-8,10H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10167273 (2019) BindingDB Entry DOI: 10.7270/Q24F1ST0
					More data for this Ligand-Target Pair