Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prolactin-releasing peptide receptor' and Ligand = 'BDBM195617'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195617 (US9206173, 5) Show SMILES C[C@H](Nc1nc2CCN(Cc2c(=O)n1N(C)C)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C26H24F4N6O2/c1-15(17-5-7-18(8-6-17)26(28,29)30)32-25-33-22-10-11-35(14-20(22)24(38)36(25)34(2)3)23(37)19-9-4-16(13-31)12-21(19)27/h4-9,12,15H,10-11,14H2,1-3H3,(H,32,33)/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-46.2	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195617 (US9206173, 5) Show SMILES C[C@H](Nc1nc2CCN(Cc2c(=O)n1N(C)C)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C26H24F4N6O2/c1-15(17-5-7-18(8-6-17)26(28,29)30)32-25-33-22-10-11-35(14-20(22)24(38)36(25)34(2)3)23(37)19-9-4-16(13-31)12-21(19)27/h4-9,12,15H,10-11,14H2,1-3H3,(H,32,33)/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair