Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prolactin-releasing peptide receptor' and Ligand = 'BDBM195634'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195634 (US9206173, 2396) Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C25H24ClF3N4O3/c1-14-12-17(6-9-20(14)26)22(34)32-11-10-21-19(13-32)23(35)33(36-3)24(31-21)30-15(2)16-4-7-18(8-5-16)25(27,28)29/h4-9,12,15H,10-11,13H2,1-3H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20	-43.9	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195634 (US9206173, 2396) Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C25H24ClF3N4O3/c1-14-12-17(6-9-20(14)26)22(34)32-11-10-21-19(13-32)23(35)33(36-3)24(31-21)30-15(2)16-4-7-18(8-5-16)25(27,28)29/h4-9,12,15H,10-11,13H2,1-3H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair