Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prolactin-releasing peptide receptor' and Ligand = 'BDBM195746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195746 (US9206173, 63) Show SMILES COn1c(N[C@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C25H22F6N4O4/c1-14(15-3-7-17(8-4-15)24(26,27)28)32-23-33-20-11-12-34(13-19(20)22(37)35(23)38-2)21(36)16-5-9-18(10-6-16)39-25(29,30)31/h3-10,14H,11-13H2,1-2H3,(H,32,33)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	-44.5	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195746 (US9206173, 63) Show SMILES COn1c(N[C@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C25H22F6N4O4/c1-14(15-3-7-17(8-4-15)24(26,27)28)32-23-33-20-11-12-34(13-19(20)22(37)35(23)38-2)21(36)16-5-9-18(10-6-16)39-25(29,30)31/h3-10,14H,11-13H2,1-2H3,(H,32,33)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	686	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair