Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM386024'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proline-rich AKT1 substrate 1 (Homo sapiens (Human))	BDBM386024 (4-{4-[1-(4-chloro-phenyl)-2-(pyrrolidin-yl)-ethyl]...) Show SMILES Clc1ccc(cc1)C(CN1CCCC1)N1CCN(CC1)c1ncnc2NCC(=O)Nc12 Show InChI InChI=1S/C22H28ClN7O/c23-17-5-3-16(4-6-17)18(14-28-7-1-2-8-28)29-9-11-30(12-10-29)22-20-21(25-15-26-22)24-13-19(31)27-20/h3-6,15,18H,1-2,7-14H2,(H,27,31)(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q26M394B
					More data for this Ligand-Target Pair