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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50118916'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl endopeptidase


(Sus scrofa)		BDBM50118916
PNG
(1,6-Bis-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-y...)
Show SMILES O=C(CCCCC(=O)N1CCC[C@H]1C(=O)N1CCCC1)N1CCCC1C(=O)N1CCCC1
Show InChI InChI=1S/C24H38N4O4/c29-21(27-17-7-9-19(27)23(31)25-13-3-4-14-25)11-1-2-12-22(30)28-18-8-10-20(28)24(32)26-15-5-6-16-26/h19-20H,1-18H2/t19-,20?/m0/s1
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PC cid
PC sid
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Similars
PubMed
n/an/a 68n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against prolyl oligopeptidase (POP) from pig brain ;value ranges from (44-110)

J Med Chem 45: 4581-4 (2002)


BindingDB Entry DOI: 10.7270/Q22R3R02
More data for this
Ligand-Target Pair