Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50134178'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Sus scrofa)	BDBM50134178 ((S)-1-{3-[(R)-2-(Pyrrolidine-1-carbonyl)-pyrrolidi...) Show SMILES O=C(NCc1ccccc1)[C@@H]1CCCN1C(=O)c1cccc(c1)C(=O)N1CCC[C@@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C29H34N4O4/c34-26(30-20-21-9-2-1-3-10-21)24-13-7-17-32(24)27(35)22-11-6-12-23(19-22)28(36)33-18-8-14-25(33)29(37)31-15-4-5-16-31/h1-3,6,9-12,19,24-25H,4-5,7-8,13-18,20H2,(H,30,34)/t24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description In vitro inhibition of prolyl oligopeptidase (POP) from pig brain				J Med Chem 46: 4543-51 (2003) Article DOI: 10.1021/jm030811o BindingDB Entry DOI: 10.7270/Q2H70F6R
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