Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50399727'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Sus scrofa)	BDBM50399727 (CHEMBL2178970) Show SMILES O=C(CCCc1ccccc1)N1C[C@H](C[C@H]1C(=O)N1CCCC1)n1cc(COCc2ccccc2)nn1 |r| Show InChI InChI=1S/C29H35N5O3/c35-28(15-9-14-23-10-3-1-4-11-23)33-20-26(18-27(33)29(36)32-16-7-8-17-32)34-19-25(30-31-34)22-37-21-24-12-5-2-6-13-24/h1-6,10-13,19,26-27H,7-9,14-18,20-22H2/t26-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of pig PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide substrate				J Med Chem 55: 9856-67 (2012) Article DOI: 10.1021/jm301060g BindingDB Entry DOI: 10.7270/Q2SN0B3S
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