Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM118341'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM118341 (US8653111, 85) Show SMILES CC(C)(C)COc1ccc(nc1)-n1[nH]cc(-n2ccnn2)c1=O Show InChI InChI=1S/C15H18N6O2/c1-15(2,3)10-23-11-4-5-13(16-8-11)21-14(22)12(9-18-21)20-7-6-17-19-20/h4-9,18H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...				US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD
					More data for this Ligand-Target Pair