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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM240931'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))
BDBM240931
PNG
(US9409892, 26)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4c(F)cccc4F)ccc3c2O)CCC1
Show InChI InChI=1S/C23H17F2N3O5/c24-15-3-1-4-16(25)20(15)33-12-5-6-13-14(9-12)17(10-26)28-18(19(13)29)21(30)27-11-23(22(31)32)7-2-8-23/h1,3-6,9,29H,2,7-8,11H2,(H,27,30)(H,31,32)
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US Patent
n/an/a 700n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair