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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM385697'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM385697
PNG
(4-{7-[(oxan-4- ylmethyl)amino]- [1,2,4]triazolo[1,...)
Show SMILES N#Cc1ccc(cc1)-c1cc(NCC2CCOCC2)cc2ncnn12
Show InChI InChI=1S/C19H19N5O/c20-11-14-1-3-16(4-2-14)18-9-17(10-19-22-13-23-24(18)19)21-12-15-5-7-25-8-6-15/h1-4,9-10,13,15,21H,5-8,12H2
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n/an/a 37n/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...

Bioorg Med Chem 16: 7424-8 (2008)


BindingDB Entry DOI: 10.7270/Q2QJ7KMD
More data for this
Ligand-Target Pair