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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM385808'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM385808
PNG
(US10287286, Example 210)
Show SMILES Nc1cc(-c2ccc(cc2F)C#N)n2ncnc2c1
Show InChI InChI=1S/C13H8FN5/c14-11-3-8(6-15)1-2-10(11)12-4-9(16)5-13-17-7-18-19(12)13/h1-5,7H,16H2
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US Patent
n/an/a 36n/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...

Bioorg Med Chem 16: 7424-8 (2008)


BindingDB Entry DOI: 10.7270/Q2QJ7KMD
More data for this
Ligand-Target Pair