Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostacyclin receptor (Homo sapiens (Human)) | BDBM50152515 (CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostacyclin receptor (Homo sapiens (Human)) | BDBM50152515 (CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting | Bioorg Med Chem 19: 6935-48 (2011) Article DOI: 10.1016/j.bmc.2011.08.065 BindingDB Entry DOI: 10.7270/Q2K35V22 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostacyclin receptor (Homo sapiens (Human)) | BDBM50152515 (CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting | Bioorg Med Chem 19: 4574-88 (2011) Article DOI: 10.1016/j.bmc.2011.06.014 BindingDB Entry DOI: 10.7270/Q2FB5398 | |||||||||||
More data for this Ligand-Target Pair |