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Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP1 subtype' and Ligand = 'BDBM50260657'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP1 subtype


(Rattus norvegicus (Rat))		BDBM50260657
PNG
(CHEMBL4062060)
Show SMILES Cc1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1
Show InChI InChI=1S/C21H17N3O2/c1-14-10-11-19-17(12-16-8-5-9-18(22-16)21(25)26)20(23-24(19)13-14)15-6-3-2-4-7-15/h2-11,13H,12H2,1H3,(H,25,26)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Watarase Research Center, Discovery Research Headquarters, Kyorin Pharmaceutical Co., Ltd., 1848, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.

Curated by ChEMBL


Assay Description
Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...

Bioorg Med Chem Lett 27: 4044-4050 (2017)


Article DOI: 10.1016/j.bmcl.2017.07.055
BindingDB Entry DOI: 10.7270/Q2PN983F
More data for this
Ligand-Target Pair