Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 947 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALLERGAN, INC. US Patent | Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALLERGAN, INC. US Patent | Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALLERGAN, INC. US Patent | Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 278 | n/a | n/a | 7.4 | 25 |
ALLERGAN, INC. US Patent | Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 8 | n/a | n/a | 7.4 | 25 |
ALLERGAN, INC. US Patent | Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM238319 (US9394273, 10 | US9394273, 8 | US9394273, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 26 | n/a | n/a | 7.4 | 25 |
ALLERGAN, INC. US Patent | Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce... | US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ | |||||||||||
More data for this Ligand-Target Pair |