Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP2 subtype' and Ligand = 'BDBM50394644'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50394644 (CHEMBL2164612) Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCC[n+]1c(C)cc(\C=C\C=C\c2ccc(cc2)N(C)C)cc1C Show InChI InChI=1S/C40H42N2O4/c1-30-27-34(12-7-6-11-32-17-21-37(22-18-32)41(3)4)28-31(2)42(30)25-26-46-38-23-19-33(29-39(38)45-5)13-10-16-35-14-8-9-15-36(35)20-24-40(43)44/h6-12,14-24,27-29H,13,25-26H2,1-5H3/p+1/b16-10+,24-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP2R expressed in chem1 cells after 2hrs by beta counting				ACS Med Chem Lett 3: 774-779 (2012) Article DOI: 10.1021/ml300191g BindingDB Entry DOI: 10.7270/Q2DZ09D3
					More data for this Ligand-Target Pair