Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP3 subtype (RAT) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by PDSP Ki Database | J Pharmacol Exp Ther 290: 551-60 (1999) BindingDB Entry DOI: 10.7270/Q2S18110 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (RAT) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by PDSP Ki Database | J Pharmacol Exp Ther 290: 551-60 (1999) BindingDB Entry DOI: 10.7270/Q2S18110 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity for mouse Prostanoid EP3 receptor | Bioorg Med Chem Lett 14: 4557-62 (2004) Article DOI: 10.1016/j.bmcl.2004.06.006 BindingDB Entry DOI: 10.7270/Q2N29XPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem 19: 4574-88 (2011) Article DOI: 10.1016/j.bmc.2011.06.014 BindingDB Entry DOI: 10.7270/Q2FB5398 | |||||||||||
More data for this Ligand-Target Pair |