Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50169548 (CHEMBL3805176) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysis | ACS Med Chem Lett 7: 306-11 (2016) Article DOI: 10.1021/acsmedchemlett.5b00455 BindingDB Entry DOI: 10.7270/Q2125VKG | |||||||||||
More data for this Ligand-Target Pair |