Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50303670'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303670 ((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21NCCS1 Show InChI InChI=1S/C24H17Cl4N3O4S3/c25-15-6-4-14(17(26)10-15)12-31-21-13(2-1-3-16(21)24(23(31)33)29-8-9-36-24)5-7-19(32)30-38(34,35)20-11-18(27)22(28)37-20/h1-7,10-11,29H,8-9,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303670 ((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21NCCS1 Show InChI InChI=1S/C24H17Cl4N3O4S3/c25-15-6-4-14(17(26)10-15)12-31-21-13(2-1-3-16(21)24(23(31)33)29-8-9-36-24)5-7-19(32)30-38(34,35)20-11-18(27)22(28)37-20/h1-7,10-11,29H,8-9,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303670 ((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21NCCS1 Show InChI InChI=1S/C24H17Cl4N3O4S3/c25-15-6-4-14(17(26)10-15)12-31-21-13(2-1-3-16(21)24(23(31)33)29-8-9-36-24)5-7-19(32)30-38(34,35)20-11-18(27)22(28)37-20/h1-7,10-11,29H,8-9,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303670 ((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21NCCS1 Show InChI InChI=1S/C24H17Cl4N3O4S3/c25-15-6-4-14(17(26)10-15)12-31-21-13(2-1-3-16(21)24(23(31)33)29-8-9-36-24)5-7-19(32)30-38(34,35)20-11-18(27)22(28)37-20/h1-7,10-11,29H,8-9,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair