BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50315969'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315969 (3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315969 (3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair