Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50315975'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315975 (3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...) Show SMILES Cc1csc(n1)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C29H28N4O4S2/c1-21-20-38-29(31-21)39(35,36)32-28(34)12-11-25-10-8-23(19-33-15-4-14-30-33)18-27(25)37-16-13-22-7-9-24-5-2-3-6-26(24)17-22/h2-10,14-15,17-18,20H,11-13,16,19H2,1H3,(H,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315975 (3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...) Show SMILES Cc1csc(n1)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C29H28N4O4S2/c1-21-20-38-29(31-21)39(35,36)32-28(34)12-11-25-10-8-23(19-33-15-4-14-30-33)18-27(25)37-16-13-22-7-9-24-5-2-3-6-26(24)17-22/h2-10,14-15,17-18,20H,11-13,16,19H2,1H3,(H,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair