Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50417196'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50417196 (CHEMBL1272084) Show SMILES Clc1ccccc1Cn1cccc(NC(=O)Nc2ccccc2I)c1=O Show InChI InChI=1S/C19H15ClIN3O2/c20-14-7-2-1-6-13(14)12-24-11-5-10-17(18(24)25)23-19(26)22-16-9-4-3-8-15(16)21/h1-11H,12H2,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...				Bioorg Med Chem Lett 20: 6744-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.137 BindingDB Entry DOI: 10.7270/Q25M65Z8
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