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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP3 subtype (RAT) | BDBM50580012 (CHEMBL5074870) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to rat EP3 receptor assessed as inhibition constant | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00594 BindingDB Entry DOI: 10.7270/Q2HT2T6X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50580012 (CHEMBL5074870) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-PGE2 from human EP3 receptor assessed as inhibition constant incubated for 2 hrs by TopCount scintillation counting method | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00594 BindingDB Entry DOI: 10.7270/Q2HT2T6X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50580012 (CHEMBL5074870) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated c... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00594 BindingDB Entry DOI: 10.7270/Q2HT2T6X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
