Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM85178' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP3 subtype
(BOVINE) | BDBM85178
(CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl...)Show SMILES CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7| Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3 | PDB
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Laboratories Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 286: 1094-102 (1998)
BindingDB Entry DOI: 10.7270/Q2KK99BC |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(BOVINE) | BDBM85178
(CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl...)Show SMILES CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7| Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Laboratories Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 286: 1094-102 (1998)
BindingDB Entry DOI: 10.7270/Q2KK99BC |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM85178
(CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl...)Show SMILES CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7| Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3 | PDB
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| Article PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
Br J Pharmacol 122: 217-24 (1997)
Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM85178
(CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl...)Show SMILES CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7| Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
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| Article PubMed
| 319 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
| |
Biochim Biophys Acta 1483: 285-93 (2000)
Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ |
More data for this Ligand-Target Pair | |