Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM238324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238324 (US9394273, 13 | US9394273, 14) Show SMILES OC(Cc1ccc2OCCOc2c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H28O6/c27-21(15-18-4-12-24-25(16-18)32-14-13-31-24)9-7-19-8-11-23(28)22(19)10-3-17-1-5-20(6-2-17)26(29)30/h1-2,4-7,9,12,16,19,21-22,27H,3,8,10-11,13-15H2,(H,29,30)/b9-7+/t19-,21?,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238324 (US9394273, 13 | US9394273, 14) Show SMILES OC(Cc1ccc2OCCOc2c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H28O6/c27-21(15-18-4-12-24-25(16-18)32-14-13-31-24)9-7-19-8-11-23(28)22(19)10-3-17-1-5-20(6-2-17)26(29)30/h1-2,4-7,9,12,16,19,21-22,27H,3,8,10-11,13-15H2,(H,29,30)/b9-7+/t19-,21?,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238324 (US9394273, 13 | US9394273, 14) Show SMILES OC(Cc1ccc2OCCOc2c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H28O6/c27-21(15-18-4-12-24-25(16-18)32-14-13-31-24)9-7-19-8-11-23(28)22(19)10-3-17-1-5-20(6-2-17)26(29)30/h1-2,4-7,9,12,16,19,21-22,27H,3,8,10-11,13-15H2,(H,29,30)/b9-7+/t19-,21?,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	142	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238324 (US9394273, 13 | US9394273, 14) Show SMILES OC(Cc1ccc2OCCOc2c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H28O6/c27-21(15-18-4-12-24-25(16-18)32-14-13-31-24)9-7-19-8-11-23(28)22(19)10-3-17-1-5-20(6-2-17)26(29)30/h1-2,4-7,9,12,16,19,21-22,27H,3,8,10-11,13-15H2,(H,29,30)/b9-7+/t19-,21?,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair