Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50333739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333739 (3-(4-(2-(1-(2-methoxyphenyl)cyclopropanecarboxamid...) Show SMILES COc1ccccc1C1(CC1)C(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(=O)N(C)C Show InChI InChI=1S/C32H34N2O3S/c1-20-18-21(2)28-24(19-20)27(29(38-28)30(35)34(3)4)23-12-10-22(11-13-23)14-17-33-31(36)32(15-16-32)25-8-6-7-9-26(25)37-5/h6-13,18-19H,14-17H2,1-5H3,(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333739 (3-(4-(2-(1-(2-methoxyphenyl)cyclopropanecarboxamid...) Show SMILES COc1ccccc1C1(CC1)C(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(=O)N(C)C Show InChI InChI=1S/C32H34N2O3S/c1-20-18-21(2)28-24(19-20)27(29(38-28)30(35)34(3)4)23-12-10-22(11-13-23)14-17-33-31(36)32(15-16-32)25-8-6-7-9-26(25)37-5/h6-13,18-19H,14-17H2,1-5H3,(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSA				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333739 (3-(4-(2-(1-(2-methoxyphenyl)cyclopropanecarboxamid...) Show SMILES COc1ccccc1C1(CC1)C(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(=O)N(C)C Show InChI InChI=1S/C32H34N2O3S/c1-20-18-21(2)28-24(19-20)27(29(38-28)30(35)34(3)4)23-12-10-22(11-13-23)14-17-33-31(36)32(15-16-32)25-8-6-7-9-26(25)37-5/h6-13,18-19H,14-17H2,1-5H3,(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor in presence of 10% HSA				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair