Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50520098'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50520098 (CHEMBL4548291) Show SMILES C[C@H](NC(=O)c1c(nnn1Cc1ccc(cc1)C(F)(F)F)-c1ccc(C)s1)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H21F3N4O3S/c1-14-3-12-20(36-14)21-22(23(33)29-15(2)17-6-8-18(9-7-17)24(34)35)32(31-30-21)13-16-4-10-19(11-5-16)25(26,27)28/h3-12,15H,13H2,1-2H3,(H,29,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Antagonist activity at human EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins follow...				J Med Chem 63: 569-590 (2020) Article DOI: 10.1021/acs.jmedchem.9b01269 BindingDB Entry DOI: 10.7270/Q2N58QRT
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50520098 (CHEMBL4548291) Show SMILES C[C@H](NC(=O)c1c(nnn1Cc1ccc(cc1)C(F)(F)F)-c1ccc(C)s1)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H21F3N4O3S/c1-14-3-12-20(36-14)21-22(23(33)29-15(2)17-6-8-18(9-7-17)24(34)35)32(31-30-21)13-16-4-10-19(11-5-16)25(26,27)28/h3-12,15H,13H2,1-2H3,(H,29,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Antagonist activity at mouse EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins follow...				J Med Chem 63: 569-590 (2020) Article DOI: 10.1021/acs.jmedchem.9b01269 BindingDB Entry DOI: 10.7270/Q2N58QRT
					More data for this Ligand-Target Pair