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Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM50501717'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 1/2


(RAT)		BDBM50501717
PNG
(CHEMBL4066021)
Show SMILES Fc1ccc(F)c(c1)-c1cnc(Cl)n1-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H8Cl2F2N2/c16-9-1-4-11(5-2-9)21-14(8-20-15(21)17)12-7-10(18)3-6-13(12)19/h1-8H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...

J Med Chem 60: 5120-5145 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00475
BindingDB Entry DOI: 10.7270/Q21G0Q81
More data for this
Ligand-Target Pair