Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM222460'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM222460 ((E)-4-[2-(4-Chlorophenyl)-4-(3,4-dimethoxybenzylid...) Show SMILES COc1ccc(\C=C2\N=C(N(C2=O)c2ccc(cc2)S(N)(=O)=O)c2ccc(Cl)cc2)cc1OC |c:8| Show InChI InChI=1S/C24H20ClN3O5S/c1-32-21-12-3-15(14-22(21)33-2)13-20-24(29)28(18-8-10-19(11-9-18)34(26,30)31)23(27-20)16-4-6-17(25)7-5-16/h3-14H,1-2H3,(H2,26,30,31)/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University; Ibn Sina National College for Medical Studies					Assay Description The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...				Bioorg Chem 72: 123-129 (2017) Article DOI: 10.1016/j.bioorg.2017.04.002 BindingDB Entry DOI: 10.7270/Q2MS3RMF
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