Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM236655'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM236655 (US9388139, 24) Show SMILES CC(C)(C)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)C(O)=O |t:4| Show InChI InChI=1S/C20H21BrN2O2/c1-20(2,3)18-12-17(13-4-8-15(21)9-5-13)23(22-18)16-10-6-14(7-11-16)19(24)25/h4-11,17H,12H2,1-3H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
German University; Southern Research Institute US Patent					Assay Description The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...				US Patent US9388139 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SFS
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