Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50048190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50048190 (CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1nccs1 Show InChI InChI=1S/C13H12N2O3S3/c1-21(17,18)15-10-6-8-2-3-11(16)9(8)7-12(10)20-13-14-4-5-19-13/h4-7,15H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50048190 (CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1nccs1 Show InChI InChI=1S/C13H12N2O3S3/c1-21(17,18)15-10-6-8-2-3-11(16)9(8)7-12(10)20-13-14-4-5-19-13/h4-7,15H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cells				Bioorg Med Chem Lett 9: 151-6 (1999) BindingDB Entry DOI: 10.7270/Q21G0KFM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50048190 (CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1nccs1 Show InChI InChI=1S/C13H12N2O3S3/c1-21(17,18)15-10-6-8-2-3-11(16)9(8)7-12(10)20-13-14-4-5-19-13/h4-7,15H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of purified recombinant human Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 9: 151-6 (1999) BindingDB Entry DOI: 10.7270/Q21G0KFM
					More data for this Ligand-Target Pair