Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2 [E165G]' and Ligand = 'BDBM175284'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175284 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-methy...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(C)cc1 Show InChI InChI=1S/C17H19N3O3S2/c1-11-3-5-13(6-4-11)17-20(16(21)12(2)24-17)19-14-7-9-15(10-8-14)25(18,22)23/h3-10,12,17,19H,1-2H3,(H2,18,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
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