Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-10' and Ligand = 'BDBM50517602'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-10 (Homo sapiens (Human))	BDBM50517602 (CHEMBL4435519) Show SMILES CC(C)C[C@H](NC(=O)c1cnc(C)s1)C(=O)N[C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r,wU:17.18,wD:29.31,4.3,(43.01,-8.6,;41.68,-9.38,;41.69,-10.91,;40.35,-8.61,;40.35,-7.07,;39.02,-6.3,;37.68,-7.07,;37.68,-8.61,;36.36,-6.3,;34.95,-6.92,;33.93,-5.77,;34.7,-4.45,;34.08,-3.04,;36.2,-4.77,;41.69,-6.3,;41.69,-4.76,;43.02,-7.07,;44.35,-6.3,;44.35,-4.76,;45.69,-3.99,;47.02,-4.77,;48.35,-4.01,;48.35,-2.47,;49.69,-1.7,;47.02,-1.69,;45.68,-2.46,;45.69,-7.07,;45.69,-8.61,;47.02,-6.3,;48.35,-7.07,;48.35,-8.61,;49.69,-9.38,;49.68,-10.92,;51.01,-11.69,;52.35,-10.92,;53.68,-11.69,;55.01,-10.92,;52.34,-9.37,;51.01,-8.61,;49.69,-6.3,;51.02,-7.07,;52.35,-6.29,;53.69,-7.07,;51.57,-4.95,;53.12,-4.95,)| Show InChI InChI=1S/C33H49N5O5S2/c1-21(2)16-28(38-33(41)30-20-35-23(4)44-30)32(40)37-29(18-25-8-6-22(3)7-9-25)31(39)36-27(14-15-45(5,42)43)17-24-10-12-26(19-34)13-11-24/h10-15,20-22,25,27-29H,6-9,16-19,34H2,1-5H3,(H,36,39)(H,37,40)(H,38,41)/b15-14+/t22?,25?,27-,28+,29+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
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