Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-2' and Ligand = 'BDBM50426992'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50426992 (CHEMBL2326260) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C36H46N8O5S/c1-24(2)19-31(34(45)40-30(17-18-50(3,48)49)20-26-9-11-28(23-37)12-10-26)41-35(46)32(21-27-13-15-29(38)16-14-27)42-36(47)33(43-44-39)22-25-7-5-4-6-8-25/h4-18,24,30-33H,19-23,37-38H2,1-3H3,(H,40,45)(H,41,46)(H,42,47)/b18-17+/t30-,31+,32+,33+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...				J Med Chem 56: 1262-75 (2013) Article DOI: 10.1021/jm3016987 BindingDB Entry DOI: 10.7270/Q2TQ62VM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50426992 (CHEMBL2326260) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C36H46N8O5S/c1-24(2)19-31(34(45)40-30(17-18-50(3,48)49)20-26-9-11-28(23-37)12-10-26)41-35(46)32(21-27-13-15-29(38)16-14-27)42-36(47)33(43-44-39)22-25-7-5-4-6-8-25/h4-18,24,30-33H,19-23,37-38H2,1-3H3,(H,40,45)(H,41,46)(H,42,47)/b18-17+/t30-,31+,32+,33+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assay				J Med Chem 56: 1262-75 (2013) Article DOI: 10.1021/jm3016987 BindingDB Entry DOI: 10.7270/Q2TQ62VM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50426992 (CHEMBL2326260) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C36H46N8O5S/c1-24(2)19-31(34(45)40-30(17-18-50(3,48)49)20-26-9-11-28(23-37)12-10-26)41-35(46)32(21-27-13-15-29(38)16-14-27)42-36(47)33(43-44-39)22-25-7-5-4-6-8-25/h4-18,24,30-33H,19-23,37-38H2,1-3H3,(H,40,45)(H,41,46)(H,42,47)/b18-17+/t30-,31+,32+,33+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assay				J Med Chem 56: 1262-75 (2013) Article DOI: 10.1021/jm3016987 BindingDB Entry DOI: 10.7270/Q2TQ62VM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50426992 (CHEMBL2326260) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C36H46N8O5S/c1-24(2)19-31(34(45)40-30(17-18-50(3,48)49)20-26-9-11-28(23-37)12-10-26)41-35(46)32(21-27-13-15-29(38)16-14-27)42-36(47)33(43-44-39)22-25-7-5-4-6-8-25/h4-18,24,30-33H,19-23,37-38H2,1-3H3,(H,40,45)(H,41,46)(H,42,47)/b18-17+/t30-,31+,32+,33+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Competitive inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK293T cells after 4 hrs by SDS-PAGE analysis in presence of BODIPY-...				J Med Chem 56: 1262-75 (2013) Article DOI: 10.1021/jm3016987 BindingDB Entry DOI: 10.7270/Q2TQ62VM
					More data for this Ligand-Target Pair