Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-5' and Ligand = 'BDBM50431005'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50431005 (CHEMBL2337884) Show SMILES CC[C@H](C)[C@H]1[C@@H](OC1=O)C(=O)N[C@H]1C[C@H]1C[C@H](NC(=O)CNC(=O)OCc1ccccc1)C=C |r| Show InChI InChI=1S/C25H33N3O6/c1-4-15(3)21-22(34-24(21)31)23(30)28-19-12-17(19)11-18(5-2)27-20(29)13-26-25(32)33-14-16-9-7-6-8-10-16/h5-10,15,17-19,21-22H,2,4,11-14H2,1,3H3,(H,26,32)(H,27,29)(H,28,30)/t15-,17+,18+,19-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assay				J Med Chem 56: 3689-700 (2013) Article DOI: 10.1021/jm4002296 BindingDB Entry DOI: 10.7270/Q25M673W
					More data for this Ligand-Target Pair