Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-5' and Ligand = 'BDBM50431008'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50431008 (CHEMBL2338318) Show SMILES CC[C@H](C)[C@H]1[C@@H](OC1=O)C(=O)N[C@H]1C[C@H]1C[C@@H](CCc1ccccc1)NC(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C32H36N2O4/c1-3-20(2)28-29(38-32(28)37)31(36)34-27-19-25(27)18-26(16-13-21-9-5-4-6-10-21)33-30(35)24-15-14-22-11-7-8-12-23(22)17-24/h4-12,14-15,17,20,25-29H,3,13,16,18-19H2,1-2H3,(H,33,35)(H,34,36)/t20-,25+,26+,27-,28-,29+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assay				J Med Chem 56: 3689-700 (2013) Article DOI: 10.1021/jm4002296 BindingDB Entry DOI: 10.7270/Q25M673W
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