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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM50010999'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proteasome subunit beta type-8


(Homo sapiens (Human))		BDBM50010999
PNG
(CHEMBL3259876)
Show SMILES O=c1oc(ns1)-c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C14H9NO2S/c16-14-17-13(15-18-14)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
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Article
PubMed
 1.40E+3n/an/an/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...

ACS Med Chem Lett 5: 405-10 (2014)


Article DOI: 10.1021/ml400531d
BindingDB Entry DOI: 10.7270/Q2PZ5BCF
More data for this
Ligand-Target Pair