Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Mdm4' and Ligand = 'BDBM143372'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Mdm4 (Homo sapiens (Human))	BDBM143372 (US8969341, 29) Show SMILES CC(C)c1c2C(N(C(=O)c2nn1CC1(O)CCN(CC1)C(C)=O)c1cc(Cl)ccc1C)c1ccc(Cl)cc1C Show InChI InChI=1S/C30H34Cl2N4O3/c1-17(2)27-25-26(33-35(27)16-30(39)10-12-34(13-11-30)20(5)37)29(38)36(24-15-22(32)7-6-18(24)3)28(25)23-9-8-21(31)14-19(23)4/h6-9,14-15,17,28,39H,10-13,16H2,1-5H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...				US Patent US8969341 (2015) BindingDB Entry DOI: 10.7270/Q2K35SC8
					More data for this Ligand-Target Pair