Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Mdm4' and Ligand = 'BDBM143411'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Mdm4 (Homo sapiens (Human))	BDBM143411 (US8969341, 60) Show SMILES CC(C)c1c2C(N(C(=O)c2nn1CCO)c1cccc(Cl)c1F)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H19Cl3FN3O2/c1-11(2)20-17-19(27-28(20)8-9-30)22(31)29(16-5-3-4-14(24)18(16)26)21(17)13-7-6-12(23)10-15(13)25/h3-7,10-11,21,30H,8-9H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...				US Patent US8969341 (2015) BindingDB Entry DOI: 10.7270/Q2K35SC8
					More data for this Ligand-Target Pair