Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Mdm4' and Ligand = 'BDBM143441'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Mdm4 (Homo sapiens (Human))	BDBM143441 (US8969341, 89) Show SMILES COC(=O)CCC1(N(C(=O)c2nn(c(C(C)C)c12)-c1ccccc1OC)c1ccc(F)c(Cl)c1)c1ccc(Cl)cc1 Show InChI InChI=1S/C31H28Cl2FN3O4/c1-18(2)29-27-28(35-37(29)24-7-5-6-8-25(24)40-3)30(39)36(21-13-14-23(34)22(33)17-21)31(27,16-15-26(38)41-4)19-9-11-20(32)12-10-19/h5-14,17-18H,15-16H2,1-4H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...				US Patent US8969341 (2015) BindingDB Entry DOI: 10.7270/Q2K35SC8
					More data for this Ligand-Target Pair