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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Mdm4' and Ligand = 'BDBM50515603'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Mdm4


(Homo sapiens (Human))		BDBM50515603
PNG
(CHEMBL4514995)
Show SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(OCc2ccccc2Cl)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C30H29Cl2N3O5/c1-30(2,3)34-28(37)27(25-22-13-10-20(31)14-24(22)33-26(25)29(38)39)35(17-36)15-18-8-11-21(12-9-18)40-16-19-6-4-5-7-23(19)32/h4-14,17,27,33H,15-16H2,1-3H3,(H,34,37)(H,38,39)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 4.67E+3n/an/an/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant MDMX (18 to 111 residues) expressed in Escherichia coli BL21 (DE3) cells measured after 30 ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111588
BindingDB Entry DOI: 10.7270/Q25H7KM3
More data for this
Ligand-Target Pair