Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Wnt-3a' and Ligand = 'BDBM50439805'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM50439805 (CHEMBL2419692 | US9227982, 2) Show SMILES Fc1ccc(CCC(=O)N(Cc2cccs2)Cc2nc3CCOCc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C22H22FN3O3S/c23-16-6-3-15(4-7-16)5-8-21(27)26(12-17-2-1-11-30-17)13-20-24-19-9-10-29-14-18(19)22(28)25-20/h1-4,6-7,11H,5,8-10,12-14H2,(H,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolin				J Med Chem 56: 6495-511 (2013) Article DOI: 10.1021/jm400807n BindingDB Entry DOI: 10.7270/Q24Q7WFB
					More data for this Ligand-Target Pair