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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM364164'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM364164
PNG
(US9856252, 56)
Show SMILES FC(F)(F)c1ccc(COc2ccc(cc2)-c2nc3ccc(nc3[nH]2)N2CCNCC2)cc1
Show InChI InChI=1S/C24H22F3N5O/c25-24(26,27)18-5-1-16(2-6-18)15-33-19-7-3-17(4-8-19)22-29-20-9-10-21(30-23(20)31-22)32-13-11-28-12-14-32/h1-10,28H,11-15H2,(H,29,30,31)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.86E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2BK1FNV
More data for this
Ligand-Target Pair